Original Research Article I Volume 5 I Issue 2 I 2017

The ratio of c-reactive protein to prealbumin to predict the mortality in patients with acute kidney injury

Mohamed Megahed, Sherif Abdelfattah, Islam Ahmed, Amr Abdelrahim

Biolife; 2017, 5(2), pp 195-200

DOI:https://doi.org/10.5281/zenodo.7364176

Abstract:

Background: Acute kidney injury (AKI) is associated with increased mortality of in hospital patients. Serum C reactive protein (CRP) is an acute-phase protein markedly increased within hours after infection or inflammation. The relation between inflammation and nutrition is complex. The serum chemistry marker 'prealbumin' is recommended to assess the nutritional status. In this study, we assessed the CRP/Prealbumin ratio as a prognostic marker in patients with AKI.

Keywords:

Critical; AKI; Prealbumin; CRP

References:

  1. Abosaif NY, Tolba YA, Heap M, Russell J, El Nahas AM.The outcome of acute renal failure in the intensive care unit according to RIFLE: model application, sensitivity, and predictability. Am J Kidney Dis 2005;46(6):1038-48.
  2. Uchino S. The epidemiology of acute renal failure in the world. Curr Opin Crit Care 2006; 12(6):538-43.
  3. Lameire N, Van Biesen W, Vanholder R:Acute renal failure.Lancet 2005; 365(9457):417-30.
  4. American Society of Nephrology Renal Research Report J Am Soc Nephrol 2005; 16(7):1886-903.
  5. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW.Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 2005; 16(11):3365-70.
  6. Fiaccadori E, Cremaschi E. Nutritional assessment and support in acute kidney injury. Curr Opin Crit Care 2009; 15(6):474-80.
  7. Fiaccadori E, Lombardi M, Leonardi S, Rotelli CF, Tortorella G, Borghetti A. Prevalence and clinical outcome associated with preexisting malnutrition in acute renal failure: a prospective cohort study. J Am Soc Nephrol 1999; 10(3):581-93.
  8. Simmons EM, Himmelfarb J, Sezer MT, Chertow GM, Mehta RL, Paganini EP, et al.Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004; 65(4):1357-65.
  9. Gaini S, Koldkjaer OG, Pedersen C, Pedersen SS. Procalcitonin, lipopolysaccharide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study. Crit care 2006; 10(2):R53.
  10. Anderson R, Schmidt R.Clinical biomarkers in sepsis.FrontBiosci (Elite Ed) 2010; 2(1):504-20.
  11. Thijs LG, Hack CE.Time course of cytokine levels in sepsis.Intensive Care Med 1995; 21(Suppl 2):S258-63.
  12. Li GS, Chen XL, Zhang Y, He Q, Wang F, Hong DQ, et al.Malnutrition and inflammation in acute kidney injury due to earthquake-related crush syndrome. BMC Nephrol 2010; 11(3):4.

Article Dates:

Received: 6 April 2017; Accepted: 23 May 2017; Published: 4 June 2017

How To Cite:

Mohamed Megahed, Sherif Abdelfattah, Islam Ahmed, & Amr Abdelrahim. (2022). The ratio of C-Reactive protein to Prealbumin to predict the mortality in patients with acute kidney injury. Biolife, 5(2), 195–200. https://doi.org/10.5281/zenodo.7364176

Download Full Paper: PDF

Logo


Logo