Original Research Article I Volume 5 I Issue 3 I 2017

Transcranial doppler as an early predictor of Delerium in septic patients and its correlation with Jagular Venous Oxygen saturation

M. Omar Elghonemi; M. Hosni; A. Safwat; M. Elsakaan

Biolife; 2017, 5(3), pp 314-320

DOI:https://doi.org/10.5281/zenodo.7364773

Abstract:

Impairment of cerebrovascular autoregulation is considered one of the most important mechanisms leading to cerebral hypo- or hyperperfusion in haemodynamically unstable septic patients. That may lead to Sepsis-associated delirium (SAD) which increases morbidity and mortality. Objective: To investigate the ability of Trans cranial Doppler (TCD) for prediction of delirium in septic patient and its relationship with jagular venous oxygen saturation (JVo2) levels.

Keywords:

Transcranial Doppler, Sepsis, Delirium, Sepsis, Jugular venous oxygen saturation.

References:

  1. Pytel P, Alexander J J. Pathogenesis of septic encephalopathy.Curr Opinoin Neurology. 2009; 22:283–287.
  2. Papadopoulos MC, Davies DC, Moss RF, Tighe D, Bennett E. Pathophysiology of septic encephalopathy, a review. Crit Care Med. 2000; 28:3019–3024.
  3. Nagaratnam N, Brakoulias V, Ng .Multiple cerebral infarcts following septic shock. J ClinNeurosci. 2002; 9:473–476.
  4. Rosengarten B, Wolff S, Klatt S, Schermuly RT. Effects of inducible nitric oxide synthase inhibition or norepinephrine on the neurovascular coupling in an endotoxic rat shock model. Crit Care. 2009;3(4):R139.
  5. Mihaylova S, Killian A, Mayer K, Pullamsetti SS, Schermuly R, Rosengarten B. Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats. J Neuroinflammation. 2012;3:183.
  6. Sharshar T, Polito A, Checinski A, Stevens RD. Septic-associated encephalopathy–everything starts at a microlevel. Crit Care. 2010;3(5):199.
  7. Bowton DL, Bertels NH, Prough DS, Stump DA. Cerebral blood flow is reduced in patients with sepsis syndrome. Crit Care Med. 1989;3(5):399–403
  8. Sharshar T, Carlier R,et al.. Brain lesions in septic shock: a magnetic resonance imaging study. Intensive Care Med. 2007;3(5):798–806
  9. Fülesdi B, Szatmári S, et al. Cerebral vasoreactivity to acetazolamide is not impaired in patients with severe sepsis. J Crit Care. 2012;3(4):337–343.
  10. Szatmári S, Végh T, Csomós A, Hallay J, Takács I, Molnár C, Fülesdi B. Impaired cerebrovascular reactivity in sepsis-associated encephalopathy studied by acetazolamide test. Crit Care. 2010;3(2):R50.
  11. Bowie RA, O’Connor PJ, Mahajan RP. Cerebrovascular reactivity to carbon dioxide in sepsis syndrome.Anaesthesia. 2003;3(3):261–265.
  12. Matta BF, Stow PJ. Sepsis-induced vasoparalysis does not involve the cerebral vasculature: indirect evidence from autoregulation and carbon dioxide reactivity studies. Br J Anaesth. 1996;3(6):790–794....

Article Dates:

Received: 3 July 2017; Accepted: 18 August 2017; Published: 1 September 2017

How To Cite:

M. Omar Elghonemi, M. Hosni, A. Safwat, & M. Elsakaan. (2022). Transcranial doppler as an early predictor of Delerium in septic patients and its correlation with Jagular Venous Oxygen saturation. Biolife, 5(3), 314–320. https://doi.org/10.5281/zenodo.7364773

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