Original Research Article I Volume 2 I Issue 1 I 2014

INFLUENCE OF IMMUNOSTIMMULANT ON ABDOMINAL MUSCLE ASPARTATE TRANSAMINASE AND ALANINE TRANSAMINASE IN MICE AGAINST HEPATITIS B

Madhuri, D; Viveka Vardhani,V

Biolife; 2014, 2(1), pp 400-406

DOI:https://doi.org/10.5281/zenodo.7198579

Abstract:

Eight groups of male Swiss albino mice mice (6 - 8 weeks old; 23 - 26g wt) were employed to study the effect of Immunostimulant, (Immunex DS) on the level of abdominal muscle transaminases against Gen Vac B vaccine. In group I, Immunex DS (IDS) was orally administered (@ 150mg/mouse) to 10 mice, in 6 groups of mice (10 in each) IDS was orally administered @ 150mg/mouse on 0 day and Gen Vac B Vaccine @ 0.07 ml/mouse (group A), 0.1ml/mouse (group B), 0.2ml/mouse (group C), 0.4ml/mouse (group D), 0.8ml/mouse (group E) and 1ml/mouse (group F) was injected on day 4 of experiment. Another group (U) of mice (ten) was kept as controls for comparison (untreated with IDS + uninfected). Two mice from each experimental (A, B, C, D, E and F) and control groups U and I (after day 7 of vaccine treatment in case of experimentals) were necropsied, from day 1-5. Abdominal muscle tissue was separated and analyzed for transaminases using standard methods.

Keywords:

ALT, AST, Abdominal muscles, Mice, Immunostimulant, Hepatitis.

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Article Dates:

Received: 13 January 2014; Accepted: 26 February 2014; Published: 8 March 2014

How To Cite:

Madhuri, D, & Viveka Vardhani,V. (2022). INFLUENCE OF IMMUNOSTIMMULANT ON ABDOMINAL MUSCLE ASPARTATE TRANSAMINASE AND ALANINE TRANSAMINASE IN MICE AGAINST HEPATITIS B. Biolife, 2(1), 400–406. https://doi.org/10.5281/zenodo.7198579