Original Research Article I Volume 2 I Issue 3 I 2014

AN ASSESSMENT ON THE PROTECTION OF GYMNEMA SYLVESTRE EXTRACTS AGAINST CASTOR OIL - INDUCED DIARRHOEA IN RATTUS NOVERGICUS

Omale James

Biolife; 2014, 2(3), pp 924-931

DOI:https://doi.org/10.5281/zenodo.7223926

Abstract:

Diarrhoea is one of the main causes of death worldwide in children and adult alike. In view of this problem, the World Health Organization has encouraged studies for treatment and prevention of diarrhoea diseases depending on traditional medicinal practices. Anti-diarrhoeal effect of crude aqueous extracts of the stem, leaf and flower of Gymnema sylvestre was assessed in castor oil-induced diarrhoea at doses of 700, 1500 and 2000 mg/kg b.w, using Rattus novergicus.

Keywords:

Castor oil, Gymnema sylvestre, anti-diarrhoea, Rattus novergicus

References:

  1. WHO (2009). The evolution of diarrhoeal and acute respiratory disease control at WGO. WGO, Geneva 1999. http//whqlibdoc.who.nq/WGO-CHI_CAH_99.12pdf
  2. WHO (1978). Ama Ata Declaration. Primary Health Care, Health for all series No. 1.
  3. WHO (1999). WHO Monographs on selected medicinal plants: Bulbus Allii capae. World Health Organization, Geneva, Pp. 289, ISBN: 92415.
  4. WHO (2011). World Health Statistics. World Health Organisation, Geneva.
  5. Cynthia, B.P., Lana, V., Kenji, S. (2008). Estimating child mortality due to diarrhoea in developing countries: A meta-analysis review. Bull. World Health Organization, 86(9): 710-717.
  6. Sumner, J. (2000). The natural history of medicinal plants. Timber press, p. 16, ISBN: 0-88192-483-0.
  7. Fawzi, M. (2013). Traditional medicine in Africa: appraisal of ten potent African medicinal plants. Evidence-Based Complementary and Alternative Medicine. Article ID617459. DO1.org/101155/2013/617459.
  8. Kanetkar, P., Singhal, R and Kamat, m. (2007). “Gymnema sylvestre: a memoir”, Journal of Clinical Biochemistry and Nutrition, 41(2): 77-81.
  9. Gurav, S., Gulkari, V., Duragkar, N., Patil, A (2007). A systematic review: Pharmacognosy, photochemistry, pharmacology and clinical applications of Gynmema sylvestre R.Br. Phamacognosy Reviews. 1:338-343.
  10. Foster, S. (2002). “Gymnema sylvestre” In: Alternative Medicine Reviews Monographs, 205-207. Thorne Research Inc.
  11. Khramov, V., Spasv, A.A and Samokhina, M.P. (2008). Chemical composition of dry extracts of Gymnema sylvestre. Pharmaceutical Chemistry Journal, 42(1): 30-32.
  12. Suisheimer, J.E., Rao, G.S. and Mclhenny, H.M. (1970). Constituents from Gymnema sylvestre leaves: Isolation and preliminary characterization of gymnemic acids. Journal of Pharmaceutical Sciences, 59(5): 622-628...

Article Dates:

Received: 11 July 2014; Accepted: 23 August 2014; Published: 12 September 2014

How To Cite:

Omale James. (2022). AN ASSESSMENT ON THE PROTECTION OF GYMNEMA SYLVESTRE EXTRACTS AGAINST CASTOR OIL – INDUCED DIARRHOEA IN RATTUS NOVERGICUS. Biolife, 2(3), 924–931. https://doi.org/10.5281/zenodo.7223926

Download Full Paper: PDF
Submit Manuscript
Join as Reviewer / Editor

Logo


Logo