Original Research Article I Volume 11 I Issue 2 I 2023

Suppression of Fertility in Male Albino Rats Following the Administration of Piper longum Crude Extracts

Buchipal Reddy and Estari Mamidala

Biolife, Volume 11, Issue 2, 2023, pp 34-39

DOI:https://dx.doi.org/10.5281/zenodo.7791768

Abstract:

Fertility control is important to keep your reproductive health in good shape. There are many different ways to do this, including contraception and infertility care. Recently, scientists have learned a lot about how male reproductive systems work, and new methods of contraception are needed to help people prevent pregnancy. The study was designed to investigate the effect of Piper longum plant extract on fertility in male albino rats. The plant components were extracted effectively with boiling water using a Soxhlet extractor. The animals were fasted overnight and given just water, after which the extracts were given orally at a dose of 5mg/kg body weight. Body weight, sperm motility, sperm count and sperm morphology were measured. The testes, epididymis, vasdeferens, seminal vesicle, and ventral prostrate were then removed, trimmed, and weighed on a torsion balance. The scientists weighed the organs of different animals and found that the animals in the high dose group (600 mg/kg bwt) lost the most weight. The animals in the moderate dose group (300 mg/kg bwt) lost the most weight, and the animals in the low dose group (100 mg/kg bwt) lost the least weight. There were no changes in the vas deferens, seminal vesicle, or prostate in any of the groups. However, the high dose group had a big problem with their sperm. The sperm in the high dose group had a lot more damage to the tail area than the head region.

Keywords:

Piper longum, fertility, soxhlet, vasdeferens, rats, prostate, sperm

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Article Dates:

Received: 18 February 2022; Accepted: 25 March 2023; Published: 1 April 2023

How To Cite:

Buchipal Reddy, & Estari Mamidala. (2023). Suppression of Fertility in Male Albino Rats Following the Administration of Piper longum Crude Extracts. Biolife, 11(2), 34–39. https://doi.org/10.5281/zenodo.7791768