Original Research Article I Volume 3 I Issue 3 I 2015

Comparative study between the effects of either dexmedetomidine or clonidine when combined with bupivacaine in thoracic epidural anaesthesia in patient undergoing thoracotomy

Asmaa Mohamed Hamza Sedky; Magda Fouad Yahia; Safaa Mohamed Helal; Nagwa Mohamed Doha; Rabab Mohamed Elhassan Ali Habib; Sally Said Donya

Biolife; 2015, 3(3), pp 739-755.

DOI:https://doi.org/10.5281/zenodo.7297879

Abstract:

Pain following thoracic surgery has been reported to be among the most intense clinical experiences. Patients experience painful wound incisions that alter chest wall mechanics and ineffective chest expansion may predispose to atelectasis, ventilation/ perfusion mismatching, hypoxemia and infection. The aim of this study is to compare the preemptive use of either dexmedetomidine or clonidine when combined with bupivacaine versus bupivacaine alone in thoracic epidural anaesthesia in patient undergoing thoracotomy.

Keywords:

dexmedetomidine , clonidine

References:

 

 
  1. Brewer RJ, Walsh GL, Anesthesia for thoracic surgery in the Oncology  patient, Anesthesiol Clin North Am, 1998;(16):605- 28.
  2. Richardson J, Sabanathan S, Shah R, Post-thoracotomy spirometric lung function: the effect of analgesia, J Cardiovasc Surg, 1999; (40):445- 56.
  3. Kruger M, McRae K, Pain management in cardiothoracic Practice, Surg Clin North Am, 1999; (79): 387- 400.
  4. Silimon M, Claus T, Huwer H, Interpleural analgesia does not influence postthoracotomy pain, Anesth Analg, 2000; (91):44- 50.
  5. Reilly JJ Jr, Preoperative and postoperative care of standard and high-risk surgical patients, Hematol Oncol Clin North Am, 1997; (11):449- 59.
  6. Katz J, Jackson M, Kavanagh BP, Acute pain after thoracic surgery predicts long-term post-thoracotomy pain, Clin J Pain , 1996; (12):50–5.
  7. Roy G., Eugene S. Fu, acute pain management of patient undergoing thoracotomy, Ann Thorac Surg , 2003; (75):1349 – 57.
  8. Wall PD, The prevention of postoperative pain, Pain,  1988; (33): 289- 9.
  9. Roy, Eugene S. Fu G. acute pain management of patient undergoing,    thoracotomy, Ann Thorac Sur ,, 2003; (75):1349-57.
  10. Ferrante FM, Acute postoperative pain management, Morgan GE Jr, 2nd , Mosby, 1998; 2331- 51.
  11. Kaukinen S, Kaukinen L, Eerola R. Preoperative and postoperative use of clonidine with neurolept anaesthesia. Acta Anaesthesiol Scand. 1978;23:113- 20.
  12. Aantaa R, Scheinin M. Alpha 2 adrenergic agents in Anaesthesia. Acta Anaesthesiol Scand 1993;37:433- 38.

Article Dates:

Received: 11 July 2015; Accepted: 25 August 2015; Published: 8 September 2015

How To Cite:

Asmaa Mohamed Hamza Sedky, Magda Fouad Yahia, Safaa Mohamed Helal, Nagwa Mohamed Doha, Rabab Mohamed Elhassan Ali Habib, & Sally Said Donya. (2022). Comparative study between the effects of either dexmedetomidine or clonidine when combined with bupivacaine in thoracic epidural anaesthesia in patient undergoing thoracotomy. Biolife, 3(3), 739–755. https://doi.org/10.5281/zenodo.7297879

Download Full Paper: PDF

Logo


Logo