Original Research Article I Volume 11 I Issue 1 I 2023

Effect of Chloroxylon swietenia Bark Extract On Lipid Profiles Of Diabetic Induced Wistar Rats

Lingaiah; Estari Mamidala; Nagaraja Rao

Biolife, Volume 11, Issue 1, 2023, pp 32-35

DOI:https://doi.org/10.5281/zenodo.7698781

Abstract:

Diabetes mellitus is a metabolic disorder and not a disease, characterized by hyperglycemia resulting from defects in insulin secretion/synthesis/induction in to the cell and insulin action or both. This investigation was designed to study the anti lipidemic profiles was investigated in diabetic induced Wistar rats treated with plant extract. Diabetes was induced after a single dose of intraperitoneal injection of Alloxan monohydrate drug (120 mg/ kg). The parameters studied were lipidprofile like Total cholesterol (TC), Triglyceride (TG), High-density lipoprotein (HDL), Low-density lipoprotein (LDL).Theresult of test drug was compared with diabetic control. Glibenclamide (600µg/kg/bw) was selected as standard hypoglycaemic drug. Administration of plant extracts also shows decreased in serum TC, TG, HDL,LDL in diabetic induced wistarrats.The results obtained from the present study revealed the potential Antilipidemic activity of selected medicinal plant extract.

Keywords:

Traditional Healers, Medicinal Plants, Ethnobotanical Survey, Diabetes Milletus, Lipid Profile .

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Article Dates:

Received: 29 December 2022; Accepted: 22 February 2023; Published online: 4 March 2023

How To Cite:

Lingaiah, Estari Mamidala, & Nagaraja Rao. (2023). Effect of Chloroxylon swietenia Bark Extract On Lipid Profiles Of Diabetic Induced Wistar Rats. Biolife, 11(1), 32–35. https://doi.org/10.5281/zenodo.7698781

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