Original Research Article I Volume 4 I Issue 4 I 2016

Study of prenatal exposure to 4-tetra octyl phenol on lipid peroxidation and activity levels of anti-oxidant enzymes in the testis of mature rats

C.H. Venkata Suneel Kumar and R. Sivasankar

Biolife; 2016, 4(4), pp 715-722

DOI:https://doi.org/10.5281/zenodo.7350845

Abstract:

4-tert-Octylphenol (OP) is major degradations products of alkylphenol ethoxylates. These chemicals are found in the waste water and sludge of sewage treatment works and river sediments. Alkylphenols are also found in drinking water. Thus, alkylphenols are widely dispersed in the environment. Several alkylphenols, including 4-tert-octylphenol have included altered sex hormone levels and hypothalamic-pituitary outcomes, impaired spermatogenesis 4-tert-octylphenol is not considered directly genotoxic.

Keywords:

4-tert-Octylphenol, Lipid Peroxidation, SOD, CAT, Testis, Mature

References:

  1. Aitken R. J. and Roman S. D. (2008). Antioxidant systems and oxidative stress in the testes. Adv Exp Med Biol, 636: 154-71.
  2. Aitken, R. J., Clarkson, J. S., Fishel, S. (1989a). Generation of reactive oxygen species, lipid peroxidation, and human sperm function. Biology of Reproduction, 41, 183-197.
  3. Armstrong J. S., Rajaskaran M., Chamulitrat W., Gatti P., Hellstrom W. J. and Sikka S.C. (1999). Characterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolism. Free Radic Biol Med, 26: 869-880.
  4. Atalay, M., and Laaksonen, D. E. (2002). Diabetes oxidative stress and physical exercise. JSSM., 1: 1-14.
  5. Atkinson, A., Roy, D. (1995). In vitro conversion of environmental estrogenic chemical bisphenol A to DNA binding metabolite(s). Biochemical and Biophysical Research Communication, 210, 424-433.
  6. Aydogan, M., Barlas, N. (2006). Effects of maternal 4-tert-octylphenol exposure on the reproductive tract of male rats at adulthood. Reproductive Toxicology, 22, 455-460.
  7. Aydogan, M., Korkmaz, A., Barlas, N., Kolankaya, D. (2010). Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats. Drug and Chemical Toxicology, 33, 193-203.
  8. Bhaskar Reddy, T. (2002). Exercise induced changes in the antioxidant enzyme status and Associated metabolic profiles of young and old rats. Ph.D. Thesis, S. V. University, Tirupati, India.
  9. Bhavanarayana  and Reddy (2013). Transplacental exposure to vinclozolin induces epididymal and testicular toxicity in adult male rats International Journal Of Pharmacy & Life Sciences Int. J. of Pharm. & Life Sci. (IJPLS), Vol. 4, Issue 3: March:, 2469-2474
  10. Porika Raju and Estari Mamidala (2015). Anti-diabetic activity of compound isolated from
    Physalis angulata fruit extracts in alloxan induced diabetic rats. The Ame J Sci & Med Res,
    2015,1(1); Pages 1 -6. doi:10.17812/ajsmr2015.11.1
  11. Bindhumol, V., Chitra, K.C. and Mathur, P.P. Bisphenol(2003). A induces reactive oxygen species generation in the liver of male rats. Toxicology.;188(2-3): 117-124.
  12. Bindu, M. P., Sreekant, K. S., Annamali, P.T., and Augusti, K. T. (2002). Effect of S-allile Cysteine  sulophoxide on lipid metabolism and free radical scavenges in alcohol fed rats. Curr. Sci., 82(6): 628-631...

Article Dates:

Received: 6 October 2016; Accepted: 29 November 2016; Published: 6 December 2016

How To Cite:

C.H. Venkata Suneel Kumar, & R. Sivasankar. (2022). Study of prenatal exposure to 4-tetra octyl phenol on lipid peroxidation and activity levels of anti-oxidant enzymes in the testis of mature rats. Biolife, 4(4), 715–722. https://doi.org/10.5281/zenodo.7350845

Download Full Paper: PDF

Logo


Logo